Can acyclovir be used in pregnancy?

Conclusion: Use of acyclovir in the first trimester does not increase birth defects, and it should be the antiviral drug of choice in early pregnancy.

Can you take acyclovir during pregnancy?

All formulations of acyclovir are assigned FDA pregnancy category C status ****, which indicates that safety in human pregnancies has not been determined; therefore, the drug should not be used during pregnancy unless the potential benefit justifies the potential risk to the fetus.

Are antivirals safe during pregnancy?

However, multiple observational studies of treatment with oral oseltamivir or zanamivir during pregnancy have shown that antiviral treatment with these medications is safe during pregnancy and does not increase risk of adverse events or adverse pregnancy outcomes (Beau et al., 2014; Dunstan et al., 2014; Ehrenstein et …

Is acyclovir safe in third trimester?

-This drug has been safely used to treat genital herpes in women in all stages of pregnancy. -Women who acquire genital herpes simplex virus (HSV) during late pregnancy should be managed in consultation with maternal-fetal medicine and infectious-disease specialists.

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What can you take for cold sores while pregnant?

Treatment of cold sores during pregnancy

The most common treatment for cold sores is docosanol (Abreva), an over-the-counter topical cream.

What category is acyclovir for pregnancy?

All formulations of acyclovir are assigned FDA pregnancy category C status ****, which indicates that safety in human pregnancies has not been determined; therefore, the drug should not be used during pregnancy unless the potential benefit justifies the potential risk to the fetus.

Does acyclovir cross the placenta?

The cord‐to‐maternal plasma concentration of acyclovir has been reported to be around 1.3,95,96 indicating that acyclovir readily crosses the placental barrier. The fetal transfer of acyclovir from maternal circulation was observed to be nonsaturable in perfused human term placenta.

Can acyclovir harm my baby?

No evidence links acyclovir or valacyclovir to serious side effects in infants born to mothers who took these drugs during pregnancy. Treatment with these drugs usually starts around the 36th week of pregnancy. It continues through delivery.

Which is better Valtrex or acyclovir?

Valacyclovir (Valtrex) and acyclovir (Zovirax) are antiviral drugs that work by interfering with viral DNA replication. Both drugs target the same viruses but valacyclovir provides longer duration of action, therefore, doses can be taken fewer times every day – this is the only real advantage.

Is it safe to take acyclovir while breastfeeding?

The American Academy of Pediatrics considers acyclovir to be safe during breastfeeding, according to the researchers. And the current study, the researchers say, confirms that Valtrex is not found in breast milk. They conclude that Valtrex is safe during breastfeeding.

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Is it bad to have a cold sore while pregnant?

Although cold sores commonly occur during pregnancy, they are generally not thought to affect the unborn baby. Nonetheless, cold sores are uncomfortable and infectious so it is advisable to treat. Cold sores are often treated with aciclovir cream which is a specific antiviral medication.

Can a mother pass cold sores to baby?

Babies can catch the cold sore virus through contact with a cold sore on another person. Therefore, people with a cold sore should avoid kissing babies or letting babies touch the sore.

Can pregnancy hormones cause cold sores?

So it’s not surprising that cold sores sometimes join the PMS party. The first step starts with understanding why you’re prone to cold sores during this time. In a word: hormones. The hormones present in your body during certain times in the menstrual cycle, as well as during pregnancy, can trigger an outbreak.

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